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- Effects of testosterone on coronary vasomotor regulation in males with coronary coronary heart illness.
- Physicians and sufferers should be conscious of the clinical penalties of anabolic steroid abuse.
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We report a case of an acute ST-segment elevation myocardial infarction in a patient with traditional cardiac threat factors using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person also had polycythemia, probably secondary to high-dose testosterone. The patient underwent successful percutaneous intervention of the right coronary artery. Physicians and sufferers ought to concentrate on the clinical consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and recommendations for monitoring. Testosterone alternative in hypogonadal males with angina improves ischaemic threshold and high quality of life. Ajayi AAL, Mathur R, Halushka PV. Testosterone improve human platelet thromboxane A2 receptor density and aggregation responses.
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Erythrocytosis has been reported as a possible effect of testosterone, which may be helpful in patients with anemia. The best risk of erythrocytosis happens with injectable types of testosterone compared with transdermal preparations, especially in supraphysiologic doses. An improve of as a lot as 44% of the baseline hematocrit has been reported .
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